With qualification for the last 16 as group winners already assured, Ferguson left most of his senior players at home for the game with Galatasaray.
As a consequence, Burak Yilmaz's second-half header earned the hosts a 1-0 win that means Galatasaray only have to match CFR Cluj's result at Old Trafford to accompany the Red Devils into the last 16.
However, Ferguson quickly dashed any suggestion Cluj may end up facing a substantially stronger team.
"We'll play a similar team against Cluj, that goes without saying," said Ferguson.
"We've qualified and there's no reason why we shouldn't use the squad."
In fact, despite the result, and yet another goal conceded from a set-piece, Ferguson declared himself reasonably satisfied with the outcome.
Eighteen year-old Nick Powell grew into the game on his first United start, coming closest for the visitors with a first-half header that struck the crossbar.
And Phil Jones came through his first full game of the season after struggling with back and knee complaints.
"We worried about set-pieces and that was the area we suffered," said Ferguson.