Meet the eight uncapped players poised to make their Ireland bow against Canada on Saturday
Joe Schmidt has named a completely new starting XV from the historic win over the All Blacks for this Saturday's clash with Canada with eight debutants likely to earn their first caps for Ireland.
Here is a profile of each of the newcomers and what you can expect from them this weekend:
Garry Ringrose (Leinster)
Place of Birth:Blackrock, Ireland
Fans have been calling for this moment for well over a year and on Saturday, Ringrose will don the number 13 shirt and make his first appearance for Ireland.
An elusive runner, the 21-year-old has bulked up in the off-season and has been in terrific form for Leo Cullen's men this season.
He has been dubbed 'the next Brian O'Driscoll' in some quarters but that is too much of a burden to place on this talented footballer. He could progress into a top class international centre.
Billy Holland (Munster)
Place of birth: Cork, Ireland
Billy Holland selection in the second row this weekend will be an extremely popular one in Irish rugby circles.
At 31 years of age, he is the oldest debutant but also the most deserving.
Holland is somewhat of a late bloomer but his form certainly justifies his selection. His tackle count and number of carries are always high. A true warrior and fine lineout performer.
Jack O'Donoghue (Munster)
Place of birth: Waterford, Ireland
Position: Back row
Just over two years since making his senior debut for Munster, O'Donoghue will pull on the number 8 shirt for Ireland on Saturday.
It's fitting that the first Irish international on home soil since the tragic death of Anthony Foley will see the scrum anchored by a Munster man.
The 22-year-old has pace and is a fine ball-carrier. He will see plenty of possession against the Canadians.
James Tracy (Leinster)
Place of birth: Dublin, Ireland
He has had to wait patiently for his big break at Leinster with Richardt Strauss and Sean Cronin standing between him and a starting berth.
Tracy began his career as a prop but Joe Schmidt advised him to switch to hooker to help him realise his international ambitions and here he is.
The 25-year-old will do himself proud when sprung from the bench this weekend.
John Ryan (Munster)
Place of birth: cork, Ireland
Position: Tighthead prop
John Ryan has rightfully been lauded as one of the most improved players in Irish rugby and will get his chance to shine in two days time.
The Munster scrum has been a potent weapon this season and much of that success is down to Ryan's exploits at tighthead.
Tadhg Furlong has put himself forward as Ireland's first-choice number 3 but Ryan is certainly in a position to challenge Finlay Bealham for a spot on the bench for the Six Nations.
Dan Leavy (Leinster)
Place of birth: Dublin, Ireland
Has played most of his rugby off the bench for Leinster this season and his displays have certainly raised eyebrows.
His cameo display in Leinster bonus-point loss to Montpelier, in very trying circumstances, suggested that the 22-year-old was ready to be blooded at international level.
His star continues to rise.
Luke McGrath (Leinster)
Place of birth: Ontario, Canada
Position: Scrum half
The 23-year-old will hope to challenge Kieran Marmion for a place on the Irish bench in the spring.
He has already established a very good working relationship with both Johnny Sexton and Joey Carbery at Leinster.
His pace and sniping ability make him a real threat around the fringes and his ability to get to each ruck quickly marks him out as a very good option as an impact sub.
Niyi Adeolokun (Connacht)
Place of birth: Ibadan, Nigeria
Adeolokun will get some reception from the Aviva Stadium crowd if he is summoned from the bench on Saturday.
His incredible journey from the AIL to becoming an Irish international is almost complete.
He has become a cult hero in Connacht in recent seasons and has developed into one of the best finishers in the Guinness Pro12.
His aerial ability and the improvement in his defensive awareness will have caught Schmidt's eye.
This weekend could be the start of something special.