Earls, who was injured for the opening two European games against Racing Metro and Edinburgh, will be partnered in the centre by James Downey, with the pair challenged to provide the cut-and-thrust to resuscitate Munster's European ambitions.
Laulala will be named on the bench as the back three of Felix Jones, Doug Howlett and Simon Zebo from last week's game against Glasgow is retained en bloc. Ronan O'Gara and Conor Murray will be the starting half-backs.
There will be changes in the pack, however. James Coughlan has returned from injury and will be restored to his No 8 spot while Peter O'Mahony will pack down at openside. Dave O'Callaghan will make his first Heineken Cup start at blindside flanker.