Teenage sensation Robbie Henshaw is set to miss his first game for Connacht this season and will instead win his first Irish U-20 cap on Friday night.
The 19-year old, who only did his Leaving Cert in June, came off the bench in the first three games of this season and since then has started all 16 games for Connacht.
He was called into the Ireland training squad for the Six Nations and made his debut for the Wolfhounds against England Saxons two weeks ago at the Sportsground.
Now he is set for his debut for the Ireland U-20s in his home town in Athlone, when Mike Ruddock's men take on England at Dubarry Park.
"Robbie has been superb for us all season," said Connacht coach Eric Elwood, whose side take on the Scarlets, also on Friday night.
"Of course we would like to have him in Llanelli, but we want to reward him as well and that's why he is being made available to the U-20s."
Elsewhere, Ulster coach Mark Anscombe will have to do without possibly 18 players ahead of Friday's Pro12 clash with a similarly weakened Ospreys outfit at Ravenhill.
squad in factfile