Colin Kaepernick led the way with his arm and with his feet, throwing for one touchdown and running for two more to lead the San Francisco 49ers to victory over the Jacksonville Jaguars 42-10 at Wembley Stadium.
Kaepernick ended up with 164 yards passing and 54 yards rushing to improve the team to 6-2. Frank Gore also ran for two scores. The Jaguars (0-8) were the "home" team, playing the first of their four-year run of regular-season NFL games in London.
Kaepernick made his first big play on San Francisco's first possession, quickly throwing to full-back Bruce Miller on the right sideline for a 43-yard gain.
A few plays later, Kaepernick scrambled for four yards on a third and five, setting up Gore for a short gain and a first down. After an incomplete pass, Gore ran 19 yards for the first touchdown.
Kaepernick took over the scoring after that, running 13 yards and diving into the corner for the second touchdown late in the first quarter, then passing to Vernon Davis in the corner of the end zone for another, and holding it and scrambling for seven yards and a touchdown.
And all in the first half. Besides a 38-yard field goal by Josh Scobee in the waning seconds of the half to make it 28-3, Jacksonville had little to be happy about. But the 49ers fumbled in their own territory late in the third quarter, giving the Jaguars their best chance to score.
But the Niners bounced right back, first with Kyle Williams returning a kick 47 yards before getting pushed out of bounds. Kendall Hunter ran 41 yards on the next play, bringing the ball to the Jacksonville 13.
Gore then ran for nine yards, two yards and the final two on three straight plays for the touchdown.
San Francisco line-backer Dan Skuta scored the final points, recovering a fumble and running it back 45 yards for a touchdown after Marcedes Lewis let the ball loose following a six-yard completion from Henne.