The eight-year-old was second in a Prestbury Park handicap in April, won a hunter chase at the track in May and was then fourth on his seasonal return last month. He is now likely to step up to Grade Three for a race named in honour of Knight, who retired in May.
Knight trained seven winners at the Cheltenham Festival and will be forever associated with the great Best Mate, winner of three Cheltenham Gold Cups. O'Brien said: "We are looking at the Henrietta Knight Chase with Bradley. He has come out of his run at The Showcase in good form and hopefully we get him to The Open in one piece.