O'Brien in for Tipp but Collins on Tribe's bench
Galway captain David Collins must play a waiting game as he bids to regain his place in the Tribesmen's defence.
Manager Anthony Cunningham has opted to field the same 15 that defeated Cork in the last round for tomorrow's All-Ireland semi-final showdown with Tipperary.
Collins missed the Leinster final defeat to Kilkenny because of a hamstring injury, but came through the last 13 minutes of their quarter-final win over the Rebels three weeks ago.
The unchanged line-up means a second start for 18-year-old Conor Whelan, who hit an impressive 1-2 on debut last time out
David Burke has recovered from a knock to his shoulder in time to renew his partnership with Andy Smith at midfield.
Meanwhile, Tipp boss Eamon O'Shea has made just one change to his side for the clash, but there is still no place in the team for Lar Corbett.
Conor O'Brien comes into the side in place of current U-21 Michael Breen, who replaced O'Brien for the Munster final win over Waterford last time out.
Tipperary ran out nine-point winners when the sides met in last year's qualifiers and a win on Sunday will set up a fifth Tipperary versus Kilkenny All-Ireland final in the last seven years.
Galway (SH v Tipperary) - C Callanan; J Coen, J Hanbury, P Mannion; A Harte, I Tannian, Daithí Burke; A Smith, David Burke; C Whelan, C Donnellan, J Glynn; J Flynn, J Canning, C Mannion.
Tipperary (SH) - D Gleeson; C Barrett, J Barry, C O'Brien; R Maher, Pádraic Maher, K Bergin; J Woodlock, S McGrath; J Forde, B Maher, Patrick Maher; J O'Dwyer, S Callanan, N O'Meara.
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