Moisturisers 'can aggravate eczema'
Published 19/10/2010 | 11:02
Using moisturising cream to treat eczema could make the condition worse, scientists claimed today.
Research from Bath University claims well-known high street branded creams can aid skin irritation.
Instead, sufferers of the painful skin condition should use oil-based treatments, the scientists said.
The university study found ointments such as aqueous cream BP reduces the thickness of healthy skin over a period of four weeks.
Originally used as a wash product, the cream is currently the most widely prescribed moisturiser for the treatment of dry skin conditions.
It is used to moisturise the skin, improving flexibility and preventing cracking in the protective outer layer, called the stratum corneum.
However, the cream contains a detergent, called sodium lauryl sulphate (SLS), which can increase the permeability of the skin barrier and cause irritation.
The study found that when healthy volunteers applied the cream to their forearms daily for a period of four weeks, the thickness of the stratum corneum was reduced by more than 10%.
The researchers anticipate that using this cream would have an even more dramatic effect on damaged skin such as that found in eczema.
Professor Richard Guy, professor of pharmaceutical sciences at Bath University, said: "The skin has a protective barrier layer of lipids, around one eighth the thickness of a sheet of paper, that stops chemicals from getting into the body and keeps moisture in.
"SLS is a detergent used to mix oils into water-based moisturisation creams to give a nice creamy texture. It's also used widely in shower gels and other cosmetics.
"Our study has found that rubbing aqueous cream containing SLS into the skin thins this protective barrier, making the skin more susceptible to irritation by chemicals.
"So to use this cream on eczemous skin, which is already thin and vulnerable to irritation, is likely to make the condition even worse."
Postgraduate researcher Manda Tsang, who worked on the project as part of her PhD studies, said: "Eczema affects around 30% of the population, an increase from around 5% a generation ago.
"This is due to a combination of genetic and environmental factors, such as central heating and carpets that can encourage dust mites, and using more creams and cosmetics that can thin the skin if used too frequently.
"Our study suggests that it might be better for eczema patients to use oil-based ointments on damaged skin."
The research has been published in the British Journal of Dermatology.