TANAISTE Eamon Gilmore is attending the UN General Assembly in New York, where the Syrian conflict and developments in Iran are top of the agenda.
The Minister for Foreign Affairs is hopeful that Ireland can lend a neutral voice to the Syrian conflict with a "reputation for fair-mindedness" and a "foreign policy position that is highly respected".
Mr Gilmore will also meet US politicians and business leaders to discuss immigration reform and foreign investment in Ireland during his five-day trip to the city.
One of the meetings includes talks with UN Secretary General Ban Ki Moon ahead of delivering a speech to the assembly at the weekend.
Mr Gilmore has echoed other international leaders, including President Barack Obama, in calling for action.
"I think it is fair to say that we share the frustration of many countries that the Security Council of the United Nations has not been able to agree a robust resolution on Syria. I hope that will be possible now, arising from the agreement on how to deal with the issue of chemical weapons, and that will be part of the discussions that will continue here today," he said.