Archbishop Charles J Brown told Massgoers in Dublin the Pope knows the recent years have been difficult for Catholic believers in Ireland.
The new papal nuncio maintained the Holy Father has been relentless in trying to make changes within the Church and help those abused by clerics.
"Again I speak from my own experience when I tell you that Pope Benedict was scandalised and dismayed as he learned about the tragedy of abuse perpetrated by some members of the clergy and of religious congregations," said Archbishop Brown, in his homily at the Pro-Cathedral of Dublin.
"He felt deeply the wounds of those who had been harmed and who so often had not been listened to.
"From the beginning, Pope Benedict was resolute and determined to put into place changes which would give the Church the ability to deal more effectively with those who abuse trust, as well as to provide the necessary assistance to those who had been victimised.
"Pope Benedict has been relentless and consistent on this front, and I assure you that he will continue to be."
Ireland has been rocked by several clerical abuse reports in recent years, including the sickening Ryan and Murphy inquiries which revealed paedophile priests were moved from parish to parish and protected from the law.
The Mass was the first celebrated by the US-born Archbishop since he presented his credentials to President Michael D Higgins during the week.
Representatives from Dublin parishes, church organisations and the diplomatic corps attended the service.