UK pharmaceutical giant GlaxoSmithKline (GSK) confirmed it is to axe a further 94 jobs, this time at an Irish shared services support centre.
The jobs will be cut over a phased basis at the GSK centre at Cork Airport Business Park.
The news follows the decision two years ago by GSK to shed 121 jobs at two of its Cork pharmaceutical production facilities.
A total of 55 jobs were axed in Currabinny and 66 jobs were shed as part of revised shift working arrangements. The firm also axed 100 jobs in 2008.
Fianna Fail leader and Cork TD Micheal Martin said the news was devastating. "The news that such a high-profile employer is shedding 94 staff comes as a major body blow to this part of the country."
GSK employs almost 1,400 people in Ireland.
The job losses follow moves by firms including Pfizer, Schering-Plough and Corden to reduce their Irish workforces in line with falling drug demand on global markets and increasing competition for branded drugs from generic rivals.