Saturday 10 December 2016

Man died of CJD 30 years after brain surgery

Louise Roseingrave

Published 01/06/2016 | 02:30

A man who contracted CJD during a brain operation when he was a child died more than 30 years later of the disease, an inquest at the Dublin Coroner’s Court heard.
A man who contracted CJD during a brain operation when he was a child died more than 30 years later of the disease, an inquest at the Dublin Coroner’s Court heard.

A man who contracted CJD during a brain operation when he was a child died more than 30 years later of the disease, an inquest heard.

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Noel Kavanagh (36) from Ballyragget, Co Kilkenny, lived a full life until he became ill in 2013 and died on October 20, 2014.

In July 1983, he underwent an eight-hour brain operation at the old Richmond Hospital on North Brunswick Street in Dublin. The surgery followed a fall from a tractor in which Mr Kavanagh, then aged five, had sustained a serious head injury.

He had a difficult recovery initially, but subsequently improved and went on to live a full and busy life, Dublin Coroner's Court heard. He enjoyed running and played soccer and was involved in the Special Olympics. He was able to manage independently and worked in a garden centre, the court heard.

In May 2013 he began to feel tired, listless and drowsy. He was brought to St Luke's Hospital in Kilkenny and later transferred to Beamount Hospital in Dublin. CT scans and a lumbar puncture were carried out and Mr Kavanagh was treated for an infection, thought to be a bacterial infection or meningitis, with antibiotics and steroids.

However, his clinical condition did not improve. He developed epilepsy and Donncha O'Brien, consultant neurosurgeon at Beaumont Hospital, said a hemispherectomy - a rare surgical procedure where half of the brain is removed - was agreed as a treatment for persistent seizures.

During this procedure, brain tissue slides were taken and sent for analysis, revealing the presence of Creutzfeldt-Jakob disease or CJD. Mr Kavanagh had contracted CJD 30 years previously due to contaminated donor graft tissue inserted during the neurosurgery performed at the old Richmond Hospital.

Coroner Dr Brian Farrell returned a narrative verdict setting out the circumstances of Mr Kavanagh's death. Dr Farrell said a variant of CJD emerged in the early 2000s related to burger meat but this case concerned infected donor tissue.

"This is a set of unfortunate circumstances. The initial head injury was not fatal, but during that treatment, Noel contracted the infection.

"A dura [brain membrane] donor graft was used and it seems that graft was infected with CJD at the time. And over the years, there were changes in Noel's brain which indicated this had been ongoing for a long time.

"The diagnosis was ultimately confirmed when he passed away," the coroner said.

Irish Independent

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