Eighty-nine jobs are to be lost with the closure of a manufacturing plant.
Diamond Innovations Ireland, which makes superabrasive products for the material removal industry, is transferring its operations from Dublin back to Ohio in the United States.
The announcement was made on the day the Government unveiled a target of creating 20,000 manufacturing jobs by 2016.
The employment drive involves encouraging start-ups with special funding and training to reduce energy, waste, tax and regulation costs as well as access to special development grants.
Diamond Innovations, a subsidiary of Sandvik AB, has been based in Ireland since 1981.
The Clonshaugh plant will close for good in September.
Company president Mark Schweizer paid tribute to the employees who he said had given great service and commitment over many years.