Doogie Howser MD (Neil Patrick Harris)
Regarded as one of the first medical dramas of the recent TV era, Doogie Howser starred Neil Patrick Harris as a 14-year-old prodigy who becomes resident surgeon at a large Los Angeles hospital. It was cancelled in 1993 after four seasons
Dr Douglas Ross (George Clooney)
Playing womanising medic Doug Ross turned struggling TV actor George Clooney into a megastar.
He didn't forget what this iconic role did for him -- Clooney made sure to put in a cameo in ER's final episode last year.
Dr Phillip Chandler (Denzel Washington)
Washington's big break was landing the part of Dr Phillip Chandler in the 80s hospital drama St Elsewhere. A regular throughout the show's eight-year span, he parlayed TV stardom into a an acclaimed movie career.
Dr Izzie Stevens
(Katherine Heigl, pictured)
Before she became a household name courtesy of Knocked Up, Heigl was a star of Grey's Anatomy. After she declined to return for the seventh season to focus on her movie ambitions, Heigl's character was killed off screen with a chronic case of metastatic melanoma.
Dr Julius Hibbert (Harry Shearer)
The Simpsons' resident doctor is supposed to be a good-natured parody of the character played by Bill Cosby on his 80s show.
He is voiced by Harry Shearer, who also plays Ned Flanders, Principal Skinner and Mr Burns.