The album reached the milestone last week, less than two years after its release.
It is the 21st album to sell 10 million copies since Nielsen SoundScan began tracking US and Canadian sales in 1991.
Adele's studio album debuted in 2011 and featured such hits as Rolling In The Deep, Someone Like You and Set Fire To The Rain.
It is the third album to reach the 10 million mark in 2012.
Adele won in all six categories she was nominated in at the Grammys earlier this year, including album of the year.