It will be the first time the singer, who recently gave birth to her first child, has performed the Bond theme live.
She said: "It's an honour to be nominated and terrifyingly wonderful to be singing in front of people who have captured my imagination over and over again. It's something I've never experienced and probably only ever will once!"
‘Skyfall’ is the first Bond theme song to be nominated for an Oscar since Sheena Easton's 'For Your Eyes Only' in 1981.
"She is currently one of the most successful recording artists in the world, and we believe that her performance of 'Skyfall' will be an exciting Oscar moment for audiences watching at the Dolby Theatre and on television screens around the world."
It is also rumored that all six Bonds - Sean Connery, George Lazenby, Roger Moore, Timothy Dalton, Pierce Brosnan and Daniel Craig – will appear together for the first time ever at the ceremony to mark the movie franchise’s 50 years.
It is believed Adele’s performance could form the centre-piece for the actors’ appearance on stage.
The 85th Academy Awards take place on February 24th.