'Worrying' new research links popular weedkiller to fatty liver disease
A new study has linked the commonly used glyphosate-based Roundup herbicide with non-alcoholic fatty liver disease in rats at 'very low' doses.
The authors of the study say it is unique in that it is the first to show a causative link between consumption of Roundup at a real-world environmental dose and a serious disease condition.
The study, by Scientific Reports, an online, open access journal from the publishers of Nature used cutting edge profiling methods to describe the molecular composition of the livers of female rats administered with an extremely low dose of Roundup weedkiller over a two-year period.
The dose of glyphosate from the Roundup administered was thousands of times below what is permitted by regulators worldwide.
The study revealed that these animals suffered from non-alcoholic fatty liver disease (NAFLD). Non-alcoholic fatty liver disease (NAFLD) is the build up of extra fat in liver cells that is not caused by alcohol. It is normal for the liver to contain some fat. However, if more than 5% - 10% percent of the liver’s weight is fat, then it is called a fatty liver (steatosis).
NAFLD affects up to 25% of people in the United States.
Symptoms of NAFLD include fatigue, weakness, weight loss, loss of appetite, nausea, abdominal pain, spider-like blood vessels, yellowing of the skin and eyes (jaundice), itching, fluid build-up and swelling of the legs and abdomen, and mental confusion.
NAFLD can progress to the more serious condition, non-alcoholic steatohepatitis (NASH). NASH causes the liver to swell and become damaged.