The major exhibition will begin on February 8 at the MAC in Belfast in partnership with the Tate art gallery in London, which owns the touring collection.
Gillian Mitchell, director of programmes at the MAC, said she was thrilled.
Three galleries will display some of Warhol's most popular images including Chairman Mao, Hamburger, Cow Wallpaper and references to the famous nightclub Studio 54 in New York City.
Warhol's work has inspired more events at the MAC ranging from a Studio 54-themed disco night featuring an original resident DJ from the club, Nicky Siano, to a live theatre production of some of his film work by the Gob Squad.
The exhibition will run until April 28 and is free to the public, although live events are ticketed.
Among the range of sponsors is public funder the Arts Council of Northern Ireland.
Chief executive Roisin McDonough said: "The venue has offered a wealth of opportunities to participate in and enjoy the arts and, with an exciting programme planned to kick start 2013, the MAC is sure to build on its success and will carry on attracting people from throughout Northern Ireland and beyond."
She added: "The Arts Council's £5.25 million capital investment in the MAC will continue to stimulate the economy here and provide a more attractive cultural tourism offering."
Since its opening last April, the MAC has seen more than 220,000 visitors to date.